Choosing the best diaper rash can make a big difference for your bundle of joy. The right diaper rash cream will leave your baby’s skin protected, moisturized and soft while preventing or even healing irritated skin. Get the wrong product, and both you and your baby could be in for some sleepless nights. We’ve reviewed several of the market’s best products to bring you our top three product brands—they are Desitin, Burt’s Bees and Babyganics. Read on to learn more about these outstanding producers of diaper rash creams..

The first brand we’d like to highlight is Desitin, which offers diaper rash creams in rapid relief, maximum strength and multi-purpose formulas. Desitin Rapid Relief is a zinc oxide-based cream that creates an instant, thin, protective barrier between your baby’s skin and her diaper. The maximum strength formula also does this while containing added ingredients to more thoroughly treat diaper rash. The multi-purpose formula also protects while nourishing the skin and promoting healing irritated skin, including diaper irritations and skin that is dry or chapped. Desitin’s products are natural, hypoallergenic and easy to apply.


  • Three strengths available
  • Hypoallergenic
  • Forms instant protective barriers

Burt’s Bees Baby Bee Diaper Ointment

Do you want a diaper rash cream that’s made from natural ingredients without parabens, phthalates and other chemicals? If so, check out Burt’s Bees Baby Bee Diaper Ointment. Available online and at many drugstores, this product is infused with almond oil, vitamin D, proteins and other natural compounds that soften and sooth a baby’s irritated skin. In addition, the regular use of this product can help to prevent diaper rashes from setting in by forming barriers and reducing friction. This product might leave behind white residues, but it’s nothing that can’t be easily washed off.


  • All-natural ingredients
  • Softens and soothes irritated skin
  • Might leave a residue


Soften and protect your baby’s delicate skin with Babyganics Diaper Rash Cream. This plant-based formula contains zinc oxide and is hypoallergenic. Made with several natural ingredients and vitamins A, D and E, this creamy product goes on easy and doesn’t leave behind any film or residue. It offers excellent protection from wet diapers and can both prevent and treat diaper rash. Available in 4-ounce tubes, you can visit the Babyganics website to locate this cream in the store nearest you. Give Babyganics Diaper Rash Cream a look if you’d like to try a plant-based solution.


  • Plant-based cream
  • Hypoallergenic
  • Contains vitamins A, D and E


Your choice of a diaper rash cream can make a big difference for the well-being of both you and your baby. These three companies are known for producing high-quality products that can prevent rashes from occurring while also offering protection against friction and skin irritation. Start with these brands and products if you need help choosing a new diaper rash cream.