For those of us who need oxygen machines, it can feel nearly impossible to get out of the house and live our lives. Thankfully a variety of portable oxygen concentrators have been built to help fill this need. The following five are among the best portable oxygen concentrators you can find on the market. Each offers you multiple benefits, including small sizes, long-lasting batteries, comfortable carrying cases, and adjustable oxygen flows. When choosing the model that is right for you, make sure to carefully read all the options and benefits to narrow it down to one that is perfect for your unique needs.

Top 5 Portable Oxygen Concentrators

  • Airsepf Focus
  • Lifechoice ActivOx 4L
  • Invacare XPO2
  • SeQual Eclipse 5
  • Respironics SimplyGo

A lightweight portable oxygen concentrator is a great way to help increase quality of life without the need to carry around heavy oxygen tanks, which can be cumbersome and difficult to transport. Keep reading to learn more about the top oxygen concentrators, so you can choose the right one for your needs and budget.

Airsep Focus

Airsep portable oxygen concentrators are some of the top options on the market. The Airsep Focus is one of their best because it offers a variety of benefits, including the new Ultra-Sense technology. This gives you more control over your flow of oxygen to create a gentler and easier to handle breathing situation. It is also just six-inches tall and five-inches wide, making it easy to carry on your hip or in your hand. Each lithium-ion battery takes just 90-minutes to charge and lasts up to three hours.

Ultra-Sense technology, fast-charging batteries, easy portability

Lifechoice ActivOx 4L

Lifechoice is another leader in portable oxygen machines and the ActivOx 4L is their standout model. It has been FAA-approved to provide you with a steady supply of oxygen. Where this particular versions stands out is in its small size. With a weight of just 4.3 pounds, it can be carried by just about anybody. Even with the three-hour external battery, the system weighs just over five pounds. With an easy-to-use carrying case and a backpack strap, this model is great for those who can’t quite handle a bulky unit and want one that is easy to carry and which lasts for most of the day. This makes it perfect for lengthy car trips.


  • Long-life battery
  • Very low weight
  • Comfortable backpack carrier

Invacare XPO2

While this Invacare model offers many of the same benefits inherent in other top-rated portable oxygen concentrators, it also comes with a variety of “pulse” settings that make it more adjustable to various conditions. For example, those who get winded but don’t suffer from a serious condition can use “one” while those with COPD, pulmonary fibrosis, or other serious problems can set it to “five” for the best effect. However, the biggest breakthrough with this model is the Invacare Sensi-Pulse Technology. This technology will automatically adjust your oxygen flow to match your activity level. In this way, you’ll never be short on breath if you are on the go or doing chores at home


  • Plenty of oxygen tubing
  • Comfortable carrying case
  • Multiple power supply options

SeQual Eclipse 5

Those who need heavy doses of oxygen typically do well with the Eclipse 5. This continuous flow portable oxygen concentrator is capable of offering continuous flow of up to three liters of oxygen per minute. However, it can be adjusted to lower levels to help suit those who don’t need such heavy concentrations to breath comfortably. One great option is the AutoSat, which adjusts to your breathing rate. As your breathing rate decreases, the flow of oxygen will be increased to compensate. This makes it possible to use this machine when napping or sleeping.


  • Adjustable pulse mode
  • High-volume output
  • Universal Cart design for easier battery access

Respironics SimplyGo

The SimplyGo is designed to suit the needs of those who need one to two liters of oxygen per minute on continuous flow or one to six liters of supplemental or “pulsed” oxygen. Its small and compact size makes it easily portable, while its rechargeable lithium-ion battery can last for hours. It’s push-button control system is easy-to-understand and use, making it perfect for a wide range of people. For those who plan on living life on the go with their portable oxygen concentrator, a handle and a set of wheels have been installed to make this slightly heavier model a little more easy to move.


  • Push-button control system
  • Travel handle and wheels
  • Rechargeable lithium-ion battery


Now that you better understand your options, you can make a better purchasing decision when deciding on a portable oxygen concentrator. Choosing between any of these five models is your best bet, as they offer the most diverse options on the market.